Results of calculating NEAR and traditional efficacy and safety variables with data obtained from a CRT in which gemifloxacin was assayed versus trovafloxacin [6].

A lower limit of 95% confidence interval above 1.0 (except for NNT and NNH) means that gemifloxacin is preferable to trovafloxacin. The minus sign in the case of NNT indicates that fewer patients need to be treated with gemifloxacin to obtain one further success; in the case of NNH, the minus sign means that fewer patients need to be treated with gemifloxacin to produce one further adverse event.