Gene-set enrichment analysis results from fgsea (https://www.bioconductor.org/packages/release/bioc/html/fgsea.html) for all RNA-seq experiments against the Hallmark gene sets from MigSigDB after 100000 permutations per experiment.
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Enrichment results represent enrichment of differentially expressed genes of candidate sgRNA against safe harbor controls for the specificed Cas9 variant (Cas9, CRISPRa). ES, enrichment score; NES, enrichment score normalized to mean enrichment of random samples of the same size; nMoreExtreme, a number of times a random gene set had a more extreme enrichment score value; size of the pathway after removing genes not present in the dataset; leadingEdge, vector with indexes of leading edge genes that drive the enrichment. (XLSX)
创建时间：
2023-03-16
