Crystal structure of phosphatidyl inositol 4-kinase II beta in complex with HH5129

Crystal structure of phosphatidyl inositol 4-kinase II beta in complex with HH5129 Descriptor: (1~{S},2~{S},4~{S},5~{R})-6-[[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-bis(oxidanylidene)-$l^{6}-phosphanyl]oxy-bis(oxidanylidene)-$l^{6}-phosphanyl]methyl-bis(oxidanylidene)-$l^{6}-phosphanyl]oxycyclohexane-1,2,3,4,5-pentol, Phosphatidylinositol 4-kinase type 2-beta,Endolysin Authors: Klima, M, Boura, E. Deposit date: 2024-11-22 Release date: 2025-12-03 Last modified: 2026-05-20 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Compounds mimicking the Michaelis-Menten transition state of the phosphatidylinositol 4-kinase. Bioorg.Med.Chem., 139, 2026