Trough concentrations of oxycodone and its metabolites.
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Abbreviations: N, number of patients; Ratio (D3 to D1), the ratio of the geometric mean trough concentration of CR oxycodone plus aprepitant on day 3 to those of CR oxycodone alone on day 1; Ratio (D3 to D2), the ratio of the geometric mean trough concentration of CR oxycodone plus aprepitant on day 3 to those of CR oxycodone alone on day 2.
Geometric mean (% coefficient variance).
Values were corrected for dose, assuming that all patients received 20 mg of oxycodone.
*Paired t-test for difference between logarithmic geometric means (two-sided).
创建时间:
2014-08-14



