Digestive Drugs Anti-Tumor Database (DDAD)

Digestive system diseases are the most common diseases in clinical diagnosis and treatment. The main therapeutic drugs are peptic ulcer drugs, which can improve gastric and duodenal ulcer. Drugs to correct gastrointestinal motor dysfunction - digestive agents, antiemetics, sports stimulants, laxatives and antidiarrheals; Drugs that protect the function of the liver and biliary system - liver protectants and antibiliants. In recent years, it has become a new idea to reactivate the clinical value of drugs that have been used in clinical practice (including drugs that are in use, no longer in use and have been clinically evaluated) through the discovery, confirmation and application of new indications.In order to integrate and evaluate numerous research resources and results, literature review and information extraction analysis were carried out, so as to construct an anti-tumor database of digestive drugs, to assist and promote the research of digestive drugs in digestive tract and cancer treatment related diseases, and to supplement the current inclusion of digestive drugs in anti-tumor aspects of old drugs and new drugs. It includes the number and classification of data collected, including the name, structural formula, structure, CAS number, relative molecular weight, type, target, cell line, cytotoxicity assessment, tumor type, mechanism of action, reference year, reference title and corresponding website source of lipid-lowering drugs. This interface supports the function of querying the contents of the above digestive drugs. Therefore, the anti-tumor database of digestive drugs will help to further explore new indications for cancer treatment in addition to the idea of "new use of old drugs" to find the efficacy of lipid-lowering drugs themselves.