ATF4 regulates MYB to increase g-globin in response to loss of β-globin [ChIP-seq]. ATF4 regulates MYB to increase g-globin in response to loss of β-globin [ChIP-seq]
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA643998
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资源简介：
Boontanrart et al model the cellular stress that occurs upon reduction in β-globin in human erythroid cells. Decrease in β-globin attenuates the eIF2aP-ATF4 pathway and results in upregulating fetal -globin. Down-regulation of ATF4 leads to decreased levels of the -globin repressor MYB through direct binding at the HBS1L-MYB intergenic region. Overall design: ATF4 ChIP-seq in HUDEP-2 and primary erythroid progenitors
创建时间：
2020-07-03
