Human CD73 (ecto 5'-nucleotidase) in complex with compound 21
收藏Protein Data Bank Japan2025-11-26 更新2026-04-19 收录
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Human CD73 (ecto 5'-nucleotidase) in complex with compound 21 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-nucleotidase, CALCIUM ION, ... Authors: Moore, J.T, Ivic, N, Lammens, A, Krapp, S, Maskos, K. Deposit date: 2025-04-24 Release date: 2025-11-12 Last modified: 2025-11-26 Method: X-RAY DIFFRACTION (2.43 Å) Cite: Discovery of ORIC-533, an Orally Bioavailable CD73 Inhibitor That Maintains Activity in High AMP Environments to Reverse Tumor Immunosuppression. J.Med.Chem., 68, 2025
创建时间：
2025-04-24
