A hostile microenvironment in tumor tissues disrupts endoplasmic reticulum homeostasis and induces the unfolded protein response (UPR). A chronic UPR in both cancer cells and tumor-infiltrating leukoc

NIAID Data Ecosystem20

CD137 costimulation counteracts TGFβ inhibition of NK cell anti-tumor function and promotes the acquisition of tissue-resident Th9-like properties [4 treatments]. CD137 costimulation counteracts TGFβ inhibition of NK cell anti-tumor function and promotes the acquisition of tissue-resident Th9-like properties [4 treatments]

癌症免疫治疗

NK细胞功能

Enhancing NK cell-based cancer immunotherapy by overcoming immunosuppression is an unmet goal. Here, we demonstrate the ability of the anti-CD137 agonist urelumab for overcoming TGF-β-mediated inhibit

NIAID Data Ecosystem60

Proteomics and RNAseq Data.xlsx

癌症免疫治疗

多组学数据

Proteomics and RNAseq Data for "Engineering pyroptotic vesicles as personalized cancer vaccines".

NIAID Data Ecosystem20