Beadarray expression analysis to identify how LILRB2 blockade may affect transcriptional networks in M(LPS) and M(IL4)

We performed Illumina microarrays to identify how LILRB2 blockade may affect transcriptional networks in M(LPS) and M(IL4). To compare M(LPS) and M(IL4) populations helped define markers and pathway networks associated with M1 vs. M2-like functional phenotypes The expression levels of transcripts in human purified CD33 myeloid cells treated with antiLILRB2 antagonistic antibody and control Ig in the presence of IL4 or LPS. Three independent replicates from three healthy donors were analyzed for each condition.