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Bl6 Ndp-KO systemic gene therapy whole cochlea samples
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创建时间：
2023-08-25
相关数据集
CRISPR-free RNA Base Editing Mediated PTC-readthrough Restores Hearing in Mice with Otof Nonsense Mutation
CRISPR-free RNA Base Editing Mediated PTC-readthrough Restores Hearing in Mice with Otof Nonsense Mutation
integrated proteome resources70
Data_Sheet_2_Recovery kinetics of dual AAV-mediated human otoferlin expression.XLSX
Deafness-causing deficiencies in otoferlin (OTOF) have been addressed preclinically using dual adeno-associated virus (AAV)-based approaches. However, timing of transduction, recombination of mRNA, an
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2020-5-10 figures raw data.zip
Mutations in voltage-gated potassium channel KCNE1 cause Jervell & Lange-Nielsen syndrome type 2 (JLNS2), resulting in congenital deafness and vestibular dysfunction. We conducted gene ther
Figshare2020-11-08 更新20
Table_2_Overloaded Adeno-Associated Virus as a Novel Gene Therapeutic Tool for Otoferlin-Related Deafness.docx
Hearing impairment is the most common sensory disorder in humans. So far, rehabilitation of profoundly deaf subjects relies on direct stimulation of the auditory nerve through cochlear implants. Howev
NIAID Data Ecosystem70
DataSheet1_Virally Mediated Connexin 26 Expression in Postnatal Scala Media Significantly and Transiently Preserves Hearing in Connexin 30 Null Mice.docx
Non-sensory cells in the sensory epithelium of the cochlea are connected extensively by gap junctions. Functionally null mutations in GJB6 (encoding Cx30) cause hearing loss in humans. In this study,
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