Rare variant kinship test (RVKT) results from two genetic studies in the Amish.

aBased on 728 pre-menopausal women from our study of mammographic density, and after standardizing by batch and adjusting for age, an estimated narrow-sense heritability of approximately 24% (for prolactin) and 34% (for free estradiol).bBased on 753 post-menopausal women from our study of mammographic density, and after standardizing by batch and adjusting for age, an estimated narrow-sense heritability of approximately 35%.cBased on 868 men and women from the HAPI Heart study, and after adjusting for age and sex, an estimated narrow-sense heritability of approximately 49%.dBased on 10,000 simulations under the null hypothesis of a purely polygenic trait architecture.