The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog 12c/j
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The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog 12c/j Descriptor: 2-cyclohexyl-1,19-dimethoxy-11,18-dioxa-1lambda5,19lambda5-diphospha-2-stannatetracyclo[18.2.1.01,6.06,10]tricosane-3,12-dione, Peptidyl-prolyl cis-trans isomerase FKBP5 Authors: Meyners, C, Walz, C, Buffa, V, Hausch, F. Deposit date: 2024-09-09 Release date: 2025-01-15 Last modified: 2025-03-19 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Conformational Plasticity and Binding Affinity Enhancement Controlled by Linker Derivatization in Macrocycles. Angew.Chem.Int.Ed.Engl., 64, 2025
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2024-09-09




