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High resolution structure of the Streptococcus pneumoniae topoisomerase IV-DNA complex with the novel fluoroquinolone Delafloxacin

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Protein Data Bank Japan2025-07-23 更新2026-04-19 收录
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High resolution structure of the Streptococcus pneumoniae topoisomerase IV-DNA complex with the novel fluoroquinolone Delafloxacin Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, DNA (5'-D(*CP*AP*TP*GP*AP*AP*T)-3'), ... Authors: Najmudin, S, Pan, X.S, Wang, B, Chayen, N.E, Fisher, L.M, Sanderson, M.R. Deposit date: 2022-12-30 Release date: 2024-01-10 Last modified: 2025-07-23 Method: X-RAY DIFFRACTION (2.393 Å) Cite: Structural basis of topoisomerase targeting by delafloxacin. Nat Commun, 16, 2025
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2022-12-30
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