Vascular integrity is essential for maintaining tissue homeostasis

Purpose: analyze the transcriptomic differences in PBS and Riociguat treated whole lung lysate Methods: C57BL6 mice were given PBS or Riociguat treatment (i.g.). 24h later, homogenize lung and extract mRNA Results: Riociguat has merely effect on normal mice lung C57BL6 mice were given PBS or Riociguat treatment (i.g.). 24h later, homogenize lung and extract mRNA. mRNA profiles of whole lung lysate were generated by sequencing.