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Tissue microenvironment shapes distinct sets of machineries to regulate ILC2 properties

NIAID Data Ecosystem2026-03-12 收录

ILC2

组织微环境免疫

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE153749 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2021-08-06

ILC2

蠕虫感染免疫

Group 2 innate lymphoid cells (ILC2s) reside in multiple tissues including lymphoid organs and barrier surfaces, and secrete type 2 cytokines including interleukin (IL)-5, IL-9 and IL-13. These cells

NIAID Data Ecosystem60

Transcriptome of human ILC2s; primary vs IL-1b-primed

ILC2

IL-1β免疫调控

ILC2s regulate type2 immune responses and protect against helminth infection. We found that ILC2s can be expanded in the presence of a combination of cytokines IL-2 and IL-1b. To better understand the

NIAID Data Ecosystem40

Transcriptome analysis of acute IL-33 or chronic HDM activated murine lung ILC2s

炎症免疫机制

ILC2

We have identified CD25high and CD25low ILC2 subsets in various mouse models of airway inflammation. Transcriptome analysis of acute IL-33 (CD25High) or chronic HDM (CD25Low) activated murine lung ILC

NIAID Data Ecosystem20

Analysis of R5-/+ and Mc5rfl/fl R5-/+ lung ILC2 transcriptomes in papain induced acute lung inflammation

炎症免疫机制

ILC2

melanocortin 5 receptor (Mc5r) have various effects in immune responses. However, the involvement of Mc5r in ILC2 functions remains unclear. We identified the genes regulated by Mc5r in lung ILC2s dur

NIAID Data Ecosystem40

Unconventional ST2- and CD127-negative lung ILC2 populations are induced by the fungal allergen Alternaria

过敏性肺部炎症

ILC2

Group 2 innate lymphoid cells (ILC2s) have been recognized for their ability to drive type 2 responses in experimental animal models in the absence of T cells. Mice intranasally challenged with Altern

NIAID Data Ecosystem30

Tissue microenvironment shapes distinct sets of machineries to regulate ILC2 properties

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