Gene expression data from epididymal fat of systemic Iah1-knockout in A/J-12SM mouse

The QTL for fatty liver was mapped on mouse chromosome 12, designated as Fl1sa. Iah1 gene is a candidate gene for Fl1sa . In mammal, Iah1 function has been largely unknown. We constructed Iah1-knockout mouse in A/J-12SM background. Iah1 gene is abundantly expressed in epididymal fat of mouse. We compared the epididymal fat's gene expressions between Iah1-WT mouse and Iah1-KO mouse. Total RNA of male Iah1-WT mice and Iah1-KO mice fed a high-fat diet for 12 weeks were extracted from epididymal fat of three mice. The RNAs form three mice were pooled and hybridized on one Affymetrix microarry.