Data from: Prevalence of depression, anxiety, adjustment disorders, and somatoform disorders in patients with age-related macular degeneration in Germany

Aims: The purpose of this study was to analyze the prevalence of
depression, anxiety, adjustment disorders, and somatoform disorders in
patients diagnosed with age-related macular degeneration (AMD) in Germany.
Methods: This study included 7,580 patients between the ages of 40 and 90
diagnosed with AMD between January 2011 and December 2014 in 1,072 primary
care practices (index date). The last follow-up was in July 2016. We also
included 7,580 controls without AMD, which were matched (1:1) to the AMD
cases by age, sex, type of health insurance (private or statutory),
physician, and Charlson comorbidity score as a generic marker of
comorbidity. The outcome of the study was the prevalence of depression,
anxiety, adjustment disorders, and somatoform disorders recorded in the
database between the index date and the end of follow-up. Results: The
mean age among subjects was 75.7 years (SD=10.1 years), 34.0% were men,
and 7.8% had private health insurance coverage. The Charlson comorbidity
index was 2.0 (SD=1.8). Depression was the most frequent disease (33.7% in
AMD patients versus 27.3% in controls), followed by somatoform disorders
(19.6% and 16.7%), adjustment disorders (14.8% and 10.5%), and anxiety
disorders (11.7% and 8.2%). Depression (OR=1.37, 95% CI: 1.27–1.47),
anxiety (OR=1.50, 95% CI: 1.35–1.67), adjustment disorders (OR=1.50, 95%
CI: 1.36–1.65), and somatoform disorders (OR=1.22, 95% CI: 1.12–1.32) were
all positively associated with AMD. Conclusion: Overall, a significant
association was found between AMD and depression, anxiety, adjustment
disorders, and somatoform disorders.