Dataset for Limit of Detection of Raman Spectroscopy Using Polystyrene Particles from 25 to 1000 nm in Aqueous Suspensions

We systematically studied the limit of detection of confocal Raman spectroscopy using polystyrene particles in a range of 25-1000 nm as models for sizes of viruses, viral particles and aggregates. Our results demonstrated that Raman spectroscopy can detect particles as small as 50 nm at a limit of detection of 1.80 x 10^12 - 8.31 x 10^12 particle/mL, and for the largest size of 1000 nm, 5.11 x 10^8 - 2.53 x 10^9 particle/mL. In this dataset, we have included the raw and processed data files associated with the results of this manuscript.