Silver-Catalyzed Tandem Hydroamination/Hydroarylation of 1‑(2‑Allylamino)phenyl-4-hydroxy-but-2-yn-1-ones to 1′‑Allylspiro[indene-1,2′-indolin]-3′-ones
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https://figshare.com/articles/dataset/Silver_Catalyzed_Tandem_Hydroamination_Hydroarylation_of_1_2_Allylamino_phenyl_4_hydroxy_but_2_yn_1_ones_to_1_Allylspiro_indene_1_2_indolin_3_ones/2264170
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资源简介：
An efficient silver
triflate-catalyzed tandem hydroamination/hydroarylation
cascade generating 1′-allylspiro[indene-1,2′-indolin]-3′-ones
from 1-(2-allylamino)phenyl-4-hydroxy-but-2-yn-1-ones
is described. The reaction conditions are mild and general in scope
and proceed to highly functionalized spiro-targets in high yield.
This novel class of molecule possesses both the privileged indene
and indolin-3-one scaffold, which may lead to possible pharmacological
applications.
创建时间：
2016-02-17
