Silver-Catalyzed Tandem Hydroamination/Hydroarylation of 1‑(2‑Allylamino)­phenyl-4-hydroxy-but-2-yn-1-ones to 1′‑Allylspiro­[indene-1,2′-indolin]-3′-ones

An efficient silver triflate-catalyzed tandem hydroamination/hydroarylation cascade generating 1′-allylspiro­[indene-1,2′-indolin]-3′-ones from 1-(2-allyl­amino)­phenyl-4-hydroxy-but-2-yn-1-ones is described. The reaction conditions are mild and general in scope and proceed to highly functionalized spiro-targets in high yield. This novel class of molecule possesses both the privileged indene and indolin-3-one scaffold, which may lead to possible pharmacological applications.