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GKRP bound to AMG0556 and Sorbitol-6-Phosphate

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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GKRP bound to AMG0556 and Sorbitol-6-Phosphate Descriptor: (2S)-2-(6-{5-[(6-aminopyridin-3-yl)sulfonyl]thiophen-2-yl}-5-chloropyridin-3-yl)-1,1,1-trifluoropropan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... Authors: Jordan, S.R, Chmait, S. Deposit date: 2014-02-04 Release date: 2014-07-30 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 5. A Novel Aryl Sulfone Series, Optimization Through Conformational Analysis. J.Med.Chem., 58, 2015

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2014-02-04
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