Serum and glucocorticoid-induced kinase 1 (SGK1) regulates blood pressure and has been implicated in inflammation and fibrosis. We have tested whether increased SGK1 activity potentiates mineralocorti
We use reverb heart specific ko mouse model to exclude the function of reverb in heart We harvest mice at 6 ZTs and snap frozen the hear samples for transcrptomic analysis.
Autism spectrum disorders (ASD) are ~4-times more common in males than females, and CHD8 (a chromatin remodeler)-related ASD shows a strong male bias (~5:1), although the underlying mechanism remains