HCV NS5B in complex with macrocyclic INDOLE INHIBITOR
收藏Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4dru
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HCV NS5B in complex with macrocyclic INDOLE INHIBITOR Descriptor: 13-cyclohexyl-3-methoxy-17,22-dimethyl-7H-10,6-(methanoiminothioiminobutanoiminomethano)indolo[2,1-a][2]benzazepine-14,23-dione 16,16-dioxide, GLYCEROL, RNA-directed RNA polymerase, ... Authors: Cummings, M.D, Vendeville, S. Deposit date: 2012-02-17 Release date: 2012-04-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure-based macrocyclization yields hepatitis C virus NS5B inhibitors with improved binding affinities and pharmacokinetic properties. Angew.Chem.Int.Ed.Engl., 51, 2012
创建时间：
2012-02-17
