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Prevalence and Evolution of Low Frequency HIV Drug Resistance Mutations Detected by Ultra Deep Sequencing in Patients Experiencing First Line Antiretroviral Therapy Failure. Human immunodeficiency virus 1

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HIV-1耐药突变

超深度测序

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA230547 数据链接链接失效反馈

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资源简介：

low-frequency HIV-1 DRMs

应用场景：

创建时间：

2013-12-04

植物病毒

超深度测序

Viruses, and in particular RNA viruses, have a notoriously inaccurate replication, making around 10-4 errors per incorporated nucleotide. However, long-term population studies have shown that virus di

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Different rates of spontaneous mutation of chloroplastic and nuclear viroids as determined by high-fidelity ultra-deep sequencing

类病毒突变率测定

超深度测序

Mutation rates vary by orders of magnitude across biological systems, being higher for simpler genomes. The simplest known genomes correspond to viroids, subviral plant replicons constituted by circul

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Characteristics of the patient samples and basic information on UDPS.

HIV耐药性

超深度测序

Footnotes a3TC; lamivudine, ABC; abacavir, AZT; zidovudine, d4T; stavudine, ddI; didanosine, ddC; zalcitabin, TDF; tenofovir, EFV; efavirenz, NNRTI; non-nucleoside reverse transcriptase inhibitor; PI;

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The prevalence of the 9 drug-resistant mutations detected by ultra-deep sequencing derived from liver tissue.

乙型肝炎病毒突变

超深度测序

(-): mutant clones less than 0.3% among total clones at each nucleotide sites. LAM: lamivudine, ADV: adefovir, ETV: entecavir.

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HIV-1 gp41 variant Q552R and L555M resistance mutations

HIV-1耐药突变

gp41蛋白

HIV-1 gp41 variant Q552R and L555M resistance mutations Descriptor: Transmembrane protein gp41 Authors: Bhardwaj, A, Khasnis, M.D, Halkidis, K, Root, M.J. Deposit date: 2016-06-01 Release date: 2016-1

Protein Data Bank Japan2023-09-27 更新50

Prevalence and Evolution of Low Frequency HIV Drug Resistance Mutations Detected by Ultra Deep Sequencing in Patients Experiencing First Line Antiretroviral Therapy Failure. Human immunodeficiency virus 1

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