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Caeruleanone A, a Rotenoid with a New Arrangement of the D‑Ring from the Fruits of <i>Millettia caerulea</i>

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NIAID Data Ecosystem2026-03-09 收录
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Caeruleanone A (1), a novel rotenoid with an unprecedented arrangement of the D-ring, was isolated with another two new analogues, caeruleanones B (2) and C (3), together with 11 known rotenoids from the fruits of Millettia caerulea. The structures of the new compounds were determined by spectroscopic data analysis, with that of 1 being confirmed by single-crystal X-ray diffraction. Compounds 2 and 3 displayed potent mitochondrial transmembrane potential inhibitory and quinone reductase induction activities.

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2015-12-17
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