Metagenomic and metaproteomic study of oral lichen planus affected and unaffected regions

In this study we have sampled the microbiota associated with the buccal mucosa of healthy individuals (N=6, H) as well as the affected (OLP) and unaffected (H-OLP) buccal mucosa from OLP patients (N=6).The microbial communities associated to the buccal mucosa of healthy and OLP patients was studied using proteomics and metagenomics. For the latter, we amplified the hypervariable region V3-V4 of the gene 16S rRNA and sequenced it using MiSeq Illumina technology.