Acetyl-CoA carboxylase (ACC) catalyzes the rate-limiting step in de novo lipogenesis, which is increased in the livers of patients with nonalcoholic steatohepatitis. GS-0976 (firsocostat), an inhibito

Figshare2020-01-28 更新20

Epigallocatechin Gallate Protects Mice against Methionine–Choline-Deficient-Diet-Induced Nonalcoholic Steatohepatitis by Improving Gut Microbiota To Attenuate Hepatic Injury and Regulate Metabolism

非酒精性脂肪性肝炎

消化道微生物组

Epigallocatechin gallate (EGCG) has been regarded as a protective bioactive polyphenol in green tea against nonalcoholic steatohepatitis (NASH), but the mechanism remains poorly deciphered. Herein, we

NIAID Data Ecosystem20

DataSheet3_Dapagliflozin protects against nonalcoholic steatohepatitis in db/db mice.ZIP

非酒精性脂肪性肝炎

糖尿病药物

Nonalcoholic fatty liver disease (NAFLD), which is the most common liver disease, is associated with type 2 diabetes mellitus and metabolic syndrome. Although there is no consensus on the treatment of

NIAID Data Ecosystem30

DataSheet_1_Poor glycaemic control and ectopic fat deposition mediates the increased risk of non-alcoholic steatohepatitis in high-risk populations with type 2 diabetes: Insights from Bayesian-network modelling.docx

2型糖尿病并发症

非酒精性脂肪性肝炎

BackgroundAn estimated 55.5% and 37.3% of people globally with type 2 diabetes (T2D) will have concomitant non-alcoholic fatty liver disease (NAFLD) and the more severe fibroinflammatory stage, non-al

NIAID Data Ecosystem20

Additional file 2 of Machine learning-based integration identifies the ferroptosis hub genes in nonalcoholic steatohepatitis

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