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Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines

ChEBI2013-09-23 更新2026-07-21 收录

干细胞心脏分化

心脏发育预测模型

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-43197 数据链接链接失效反馈

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资源简介：

Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines

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创建时间：

2013-09-23

干细胞心脏分化

Wnt信号通路调控

Efficient directed cardiac induction of human embryonic stem cells requires an intermediate inhibition of WNT signaling, shortly after the initial induction of mesoderm. To reveal the significance of

NIAID Data Ecosystem70

Analysis of downstream effects of endogenous WNT signaling during cardiac differentiation of human ES cells. Homo sapiens

干细胞心脏分化

Wnt信号通路调控

WNT signaling inhibition at an intermediate stage of differentiation is a key requirement for cardiac induction of human ES cells, suggesting that endogenous WNT activity interferes with cardiomyocyte

NIAID Data Ecosystem40

Expression data from differentiating murine embryonic stem cells

干细胞心脏分化

基因表达调控

Various substances have been reported to enhance the cardiac differentiation of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Ascorbic Acid had a cardiogenic effect in mESC C

NIAID Data Ecosystem20

table_genes_counts_RPKM

干细胞心脏分化

RNA-seq基因表达

This table contains all the counts and RPKM values of genes identified on RNA-seq of hESC cardiac differentiation, including Ribosome-free and Polysome-bound fractions.

NIAID Data Ecosystem40

Comparative cardiac induction time-courses using WT, EOMES KO, and EOMES TET-ON human ES cells

干细胞心脏分化

EOMES基因

This study compares cardiac induction time-courses using (i) wild-type hESCs subjected to a standard directed differentiation protocol, (ii) EOMES knockout hESCs subjected to the same protocol, and (i

NIAID Data Ecosystem20

Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines

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