Natural genetic variation perturbs collaborative transcription factor binding required for enhancer selection and function
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE46494
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Natural genetic variation between two mouse strains was used as a natural mutagenesis screen to test various aspects of the proposed model for enhancer selection and function. Chromatin marks H3K4me2, H3K27Ac, and transcription factors PU.1, C/EBPa, and p65 were assessed by ChIP-Seq and GRO-Seq and RNA-Seq were used to measure gene expression in C57BL6/J and BALBc/J inbred mouse strains
创建时间:
2019-05-15



