Active Metabolite of Aeruginascin (4-Hydroxy‑<i>N</i>,<i>N</i>,<i>N</i>‑trimethyltryptamine): Synthesis, Structure, and Serotonergic Binding Affinity
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The putative active metabolite of aeruginascin, a naturally occurring tryptamine of “magic mushrooms,” has been synthesized and structurally characterized. Competitive radioligand binding assays demonstrate that it has a high affinity at human serotonin receptors 5-HT1A, 5-HT2A, and 5-HT2B, though it does not bind at the 5-HT3 receptor, where activity was previously predicted.
创建时间:
2020-07-02



