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Role of Flk1 in pulmonary arterial hypertension [Flox]

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NIAID Data Ecosystem2026-05-01 收录
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To investigate the role of Flk1 in pulmonary arterial hypertension, we generated mice lacking Flk1 specifically in vascular endothelial cells. We exposed these mice to hypoxia and collected Flk1-KO endothelial cells by FACS for RNA-seq. Overall design: The mRNA profiles of Flk1-KO endothelial cells in Normoxia or Hypoxia were generated by FACS-sorting and RNA-sequencing using MoFlo XDP (Beckman coulter) and NextSeq500 (Illumina).

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2023-08-26
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