DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells
收藏NIAID Data Ecosystem2026-05-01 收录
下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1077865
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资源简介：
DHX9 deficiency led to abnormal R-loops (RNA:DNA hybrids) accumulation, resulting in genomic instability and the cGAS-STING-mediated inflammatory response, which together impaired ISC function and contributed to the pathogenesis of IBD.
创建时间：
2024-02-19
