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Crystal structure of human PAICS in complex with inhibitor 69

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Protein Data Bank Japan2024-01-31 更新2026-03-21 收录
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Crystal structure of human PAICS in complex with inhibitor 69 Descriptor: (2~{S})-2-[[5-azanyl-1-[(2~{R},3~{R},4~{S},5~{R})-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]imidazol-4-yl]car bonylamino]butanedioic acid, 2-azanyl-~{N}-[2-bromanyl-5-[4-[3-(dimethylamino)propylsulfonyl]piperazin-1-yl]phenyl]-1,3-oxazole-4-carboxamide, Multifunctional protein ADE2 Authors: Skerlova, J, Marttila, P, Unterlass, J, Jemth, A.-S, Henriksson, M, Wakchaure, P, Grube, M, Warpman Berglund, U, Homan, E, Helleday, T, Stenmark, P. Deposit date: 2020-10-06 Release date: 2022-04-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Cellular and biochemical validation of a potent PAICS inhibitor To Be Published
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