asymmetric mTNF-alpha hTNFR1 complex
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asymmetric mTNF-alpha hTNFR1 complex Descriptor: 1-{[2-(difluoromethoxy)phenyl]methyl}-2-methyl-6-[6-(piperazin-1-yl)pyridin-3-yl]-1H-benzimidazole, Tumor necrosis factor, Tumor necrosis factor receptor superfamily member 1A Authors: Arakaki, T.L, Fox III, D, Edwards, T.E, Foley, A, Ceska, T. Deposit date: 2020-11-10 Release date: 2021-01-13 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF. Nat Commun, 12, 2021
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2020-11-10
