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Non-breast/ovarian tumors in germline BRCA1/2 carriers

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下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1032151
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资源简介:
Breast and ovarian tumors in germline BRCA1/2 carriers undergo allele-specific loss of heterozygosity, resulting in homologous recombination deficiency (HRD) and sensitivity to poly-ADP-ribose polymerase (PARP) inhibitors. This study investigated whether biallelic loss and HRD also occur in primary nonbreast/ovarian tumors that arise in germline BRCA1/2 carriers.
创建时间:
2023-10-25
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