Rpe65

ENCODES a protein that exhibits all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity; all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity (ortholog); cardiolipin binding (ortholog); INVOLVED IN camera-type eye development; circadian rhythm; neural retina development; PARTICIPATES IN retinoid cycle metabolic pathway; altered retinoid cycle metabolic pathway; retinitis pigmentosa pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; adrenocorticotropic hormone deficiency (ortholog); autistic disorder (ortholog); FOUND IN cell body; cytoplasm (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acrylamide

编码一种展现全反式视黄酰酯水解酶、形成11-顺式视黄醇活性；全反式视黄酰棕榈酸水解酶、形成11-顺式视黄醇活性（同源酶）；卡迪罗宾结合（同源酶）；参与照相机型眼发育；昼夜节律；神经视网膜发育；参与视黄醇代谢途径；视黄醇代谢途径改变；视网膜色素变性途径；与实验性糖尿病伴发；肾上腺皮质激素缺乏（同源酶）；自闭症（同源酶）；存在于细胞体；细胞质（同源酶）；内质网膜（同源酶）；与17β-雌二醇、6-丙基-2-硫尿嘧啶；丙烯酰胺相互作用。