Additional file 1 of Gut microbiome of helminth-infected indigenous Malaysians is context dependent

Additional file 1: Table S1. MaAsLin2 results of the bacterial taxa differentially abundant between OA and KL subjects independent of village, age, and sex as covariates. Table S2. Relative impact of village, helminth infection and Trichuris infection on gut microbiome dissimilarity across samples (ADONIS, ANOSIM, and Betadisper; permutation = 999) in the cross-sectional analysis. Table S3. MaAsLin2 results of the bacterial taxa that are independent and associated with the interaction between helminth and village. Table S4. Relative impact of deworming on gut microbiome dissimilarity of different group of Orang Asli samples based on their microbiome data in pre and post anthelmintic treatment (ADONIS, ANOSIM, and Betadisper; permutation = 999). Table S5. MaAsLin2 results of the bacterial taxa that are altered by treatment response, controlling for infection status and village as fixed effects. Table S6. MaAsLin2 results of the bacterial taxa that are associated with treatment response, associated with helminth status or not, correcting for village as a covariate. Table S7. Relative impact of the deworming on gut microbiome dissimilarity of different group of Orang Asli samples based on their gut microbiome data in pre, 21-day, and 42-day post- anthelmintic treatment (ADONIS, ANOSIM, and Betadisper; permutation = 999). Table S8. Spearman correlation analysis on the growth rate (GRiD score) of the bacterial species with Trichuris burden among the pre-treatment samples. Table S9. Spearman correlation analysis on the growth rate (GRiD score) of the bacterial species with Trichuris burden among the Responders. Table S10. MaAsLin2 results of the bacterial replication (based on GRiD score) that are associated with Trichuris infection while controlling for treatment group and villages.