INTESTINAL EPITHELIUM'S MORPHOFUNCTIONAL IMPORTANCE IN BOTH NORMAL AND ULCERATIVE COLITIS

Time in the normal functioning of the system of diffuse endocrine cells of the mucous membrane of the digestive tract is important . Endocrine cells of the gastrointestinal tract produce a number of biologically active substances with a wide range of local and systemic effects, which ultimately affect the growth and development of the organism. Morphological changes in the diffuse endocrine system of the alimentary tract of female rats with chronic liver damage have been studied by many scientists. Other authors have examined the characteristic changes in the diffuse endocrine system of the alimentary tract of the offspring of female rats with chronic intestinal inflammation. One of the most important issues of modern morphology is the genesis, differentiation, structure and cytophysiology of tissues under normal functioning conditions and pathology. The study of these problems allows further development of cytology, histology, endocrinology, embryology and a deeper understanding of the processes occurring in clinical pathology. In this regard, it is related to the formation, structure and differentiation of the endocrine apparatus of the large intestine in the process of phylo- and ontogenesis of the intestinal epithelium of humans and vertebrates under normal, experimental conditions and in certain types of gastrointestinal tract (GI) pathologies. issues are considered.