con7 regulates the development of Penicillium oxalicum fungi and the expression of chitinase and cellulolytic genes

The goals of this study are to compare different gene expressions for Penicillium oxalicum wild type strain (WT) and Con7 destruction strain (con7-A) under conditions of 2% glucose,2% glycerol or 1% bran + 1% microcrystalline cellulose as carbon source. The results of correlation analysis between each sample showed that the gene expression level of con7-A was significantly different from that of the WT strain. The destruction of con7 significantly affect the expression levels of sporulation process genes and the expression of chitinase and cellulase-encoding genes. Overall design: Examination of differential gene expressions by digital gene expression tag profiling in Penicillium oxalicum wild type strain, con7 destruction mutant strains in 24h in modifeid Mendal's medium with 2% glucose,2% glycerol or 1% bran + 1% microcrystalline cellulose as carbon sources. Three replicates were included for each samples.