Numerical data underlying Fig 1A–1C, 1E and 1F; Fig 2B and 2D; Fig 3C–3G; Fig 5A–5F; Fig 6A and 6C; Fig 7A–7C; Fig 8A and 8B; and S1A–S1D and S1F and S1G Fig; S3 Fig; S6 Fig; S7 Fig; S8A–S8C Fig and S9A–S9C Fig.

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