Splice-site variants of the breast cancer susceptibility gene ATM. BRIDGES_Project-2

Folder: 1.Sequences - Sub-folder cDNA. Transcript Sequencing. Sub-folders: - ATM_19-22: 31 *.ab1 files of transcripts generated by variants introduced into minigene mgATM_19-22 - ATM_41-44: 15 *.ab1 files of transcripts generated by variants introduced into minigene mgATM_41-44 - ATM_55-63: 32 *.ab1 files of transcripts generated by variants introduced into minigene mgATM_55-63 - Sub-folder: Minigenes. Sequence files of wild type and mutant constructs. Sub-folders: - ATM_19-22: 17 *.ab1 files. - ATM_41-44: 11 *.ab1 files. - ATM_55-63: 25 *.ab1 files. • Folder: 2.Fragment_Analysis. Fluorescent Fragment Analysis of splicing assays. Sub-folders: - ATM_19-22: 53 *.fsa files of fluorescent fragment analysis of variant-spicing assays. - ATM_41-44: 30 *.fsa files of fluorescent fragment analysis of variant-spicing assays. - ATM_55-63: 72 *.fsa files of fluorescent fragment analysis of variant-spicing assays.