Database - Open data collection - Framework and case study with an HPV cohort study

The objective of this article is to report on a new Open Collection and Big Data Framework (OCoBiD), where data from a prospective cohort of patients screened for Human papillomavirus (HPV) reports data in real time. This system is augmented by a number of mechanisms to ensure that the data is not only substantially enriched by other data sets and real-time data quality control, but also enhanced through real-time modeling and reporting of the resulting information. Given its objective of serving as a framework for other projects involving reproducible research and open data collection, all of its scripts and code are made made available within public repositories outlined throughout our article.