Structure of Bace-1 (Beta-Secretase) in complex with : N-(3-((1R,5S,6R)-3-amino-5-methyl-2-oxa-4-azabicyclo[4.1.0]hept-3-en-5-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide
收藏Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Structure of Bace-1 (Beta-Secretase) in complex with : N-(3-((1R,5S,6R)-3-amino-5-methyl-2-oxa-4-azabicyclo[4.1.0]hept-3-en-5-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide Descriptor: Beta-secretase 1, GLYCEROL, IODIDE ION, ... Authors: Sickmier, E.A. Deposit date: 2018-01-08 Release date: 2018-02-21 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Diastereoselective synthesis of fused cyclopropyl-3-amino-2,4-oxazine beta-amyloid cleaving enzyme (BACE) inhibitors and their biological evaluation. Bioorg. Med. Chem. Lett., 28, 2018
创建时间：
2018-01-08
