Human RSVA-ON1, the only genotypepresent during 2019–2020 winter season inRiyadh, Saudi Arabia: a retrospective study: supplementary materials

Aim: The study aimed to analyze human respiratory syncytial virus (hRSV) strains in nasopharyngealaspirates obtained retrospectively. Materials & methods: Clinical information of ARI patients (n = 53)was accessed and 2nd hypervariable region of G protein gene of RSV was sequenced and analyzed.Results: Cough (98.1%), fever 40 (75.4%) and shortness of breath 32 (60.3%) were the common symptom.Sequence determination (n = 45) categorized all the strains in ON1 genotype. Potential O- and Nglycosylationwere observed at some sites and purifying selections were observed at 274 and 320 codonpositions. Conclusion: The study reports replacement of other RSVA genotypes with ON1. The futurecourse of studies should emphasize on clinical implications of presence of hRSVA-ON1 genotype in a givenpopulation.