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TNF plays a crucial role in inflammation by signaling via T cell TNFR2 [bulkRNA-seq]

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE188160
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资源简介:
TNF regulates the inflammatory cytokine secretion from CD4+ T cells in vitro. In vitro experiment (Bulk seq): Naïve CD4+ T cells from WT or Tnfr2-/- mice were isolated from spleen and stimulated with anti-CD3/CD28 for 3 days in the presence of the different combinations of cytokines (WT: TNF+TGF-β, Tnfr2-/-: TNF+TGF-β; WT: IL-6+TGF-β) followed by bulk RNA sequence. Each experimental condition was done triplicates and analyzed.
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2022-02-07
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