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Single-cell Atlas Reveals Fatty Acid Metabolites Regulate the Functional Heterogeneity of Mesenchymal Stem Cells

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP306991
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Here, using scRNA-seq on bone marrow MSCs, we identified pre-MSCs and lineage-committed MSC clusters, and revealed their potential regulatory mechanisms in MSC lineage commitment. Our data indicated a novel potential role of MSCs responding to fatty acid treatment, which could be applied to in vitro culture. Overall design: Single-cell RNA-seq on bone marrow MSCs
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2021-05-08
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