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Transcription profiling by array of mice with liver-specific expression of hypoxia inducible factor, or inactivated von Hippel-Lindau tumor suppressor

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The effects of constitutively active Hypoxia Inducible Factor (HIF) and inactivated von Hippel-Lindau tumor suppressor gene product (pVHL) were examined in a mouse model. Conditionally expressed, constitutively active HIF-1a and HIF-2a were compared with inactivated pVHL.

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