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Identification of Pax8-BBOX1 epigenetic axis in driving tumor distant metastasis

NIAID Data Ecosystem2026-05-10 收录

肿瘤转移机制

表观遗传调控

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP485913 数据链接链接失效反馈

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资源简介：

In this item, we utilized murine tumor cell lines (Renca or 4T1) to explore the epigenetic regulations of Pax8-BBOX1 axis.

应用场景：

创建时间：

2026-03-03

肝病相关单核细胞功能障碍

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BACKGROUND/ AIMS: Severe forms of alcoholic liver disease are associated with increased susceptibility to infections largely due to immune dysfunction. In this study, we analyze the phenotypic, molecu

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Transcriptional Dynamics of Skeletal Muscle in Obesity (PRJCA023478)

肥胖相关转录组学

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Skeletal muscle is a metabolically active organ, but it remains largely unexplored in obesity. Here, we used diet-induced mice as obesity model to investigate the effect of obesity on muscle transcrip

NIAID Data Ecosystem00

ARID1B regulates BCL11B-mediated non-canonical Activin signaling to maintain mesenchymal stem cell homeostasis in the mouse incisor [scRNA-seq]

干细胞稳态

表观遗传调控

ARID1B is a epigenetic regulator. We used the scRNA sequencing to analysis the role of ARID1B in regulating mouse incisor tissue homeostasis. Single-cell transcriptomes were obtained from the digested

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mRNA profiling of Pontin WT and RA under glucose starvation

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葡萄糖饥饿应激

To determine which genes are affected by methylated Pontin, we performed RNA-sequencing (RNA-seq) in Pontin WT and RA MEFs after glucose starvation. Overall design: mRNA expression profiles of Pontin

NIAID Data Ecosystem10

DNMT3A Reads and Connects Histone H3K36me2 to DNA methylation [RNA-seq]

表观遗传调控

甲基化反应机制

DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

NIAID Data Ecosystem00

Identification of Pax8-BBOX1 epigenetic axis in driving tumor distant metastasis

资源简介：

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