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Pri-miRNA identification by generating a Drosha null/conditional-null mouse model.

ChEBI2015-02-09 更新2026-07-21 收录

条件性基因敲除

microRNA生物合成

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-55735 数据链接链接失效反馈

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Pri-miRNA identification by generating a Drosha null/conditional-null mouse model.

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创建时间：

2015-02-09

microRNA生物合成

基因功能研究

Dicer ribonucleases, which generate small RNAs for the RNA interference (RNAi) and microRNA (miRNA) pathways, often have an N-terminal DExD helicase subdomain (also called HEL1). In the mammalian Dice

NIAID Data Ecosystem100

Supplementary Material for: Gene Co-Expression Network Analysis Implicates microRNA Processing in Parkinson’s Disease Pathogenesis

帕金森病分子机制

microRNA生物合成

Background: Recent advances in genetics have provided insights into important inherited causes of Parkinson’s disease (PD), but the underlying biological mechanisms are still incompletely understood.

NIAID Data Ecosystem60

Liveborn offspring from breeding of XPorcn-ex3-7flox/X mice to 3 different Cre strains.

小鼠模型

条件性基因敲除

Liveborn offspring from breeding of XPorcn-ex3-7flox/X mice to 3 different Cre strains.

Figshare2015-12-02 更新50

Tumor Spectrum, Tumor Latency and Tumor Incidence of the Pten -Deficient Mice

基因功能研究

条件性基因敲除

BackgroundPten functionally acts as a tumor suppressor gene. Lately, tissue-specific ablation of Pten gene in mice has elucidated the role of Pten in different tumor progression models. However, a tem

NIAID Data Ecosystem70

DGCR8 is required for microRNA maturation. Mus musculus

microRNA生物合成

基因功能验证

To determine whether DGCR8 is required for maturation of all miRNAs, we performed miRNA microarray analysis. Using RNA from wild-type ES cells as our reference sample, we observed a global loss of miR

NIAID Data Ecosystem50

Pri-miRNA identification by generating a Drosha null/conditional-null mouse model.

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