Deep distributed computing to reconstruct extremely large lineage trees

NIAID Data Ecosystem2026-03-13 收录

系统发育树重建

定向进化

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https://www.ncbi.nlm.nih.gov/sra/SRP292142 数据链接链接失效反馈

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资源简介：

High-throughput amplicon sequencing data of in vitro sequence evolution assays using error-prone PCR

创建时间：

2022-01-12

The Jukes-Cantor Model and Phylogenetic Invariants

分子建模

系统发育树重建

In this presentation, I explored the Jukes-Cantor model (JC69), a foundational model in molecular evolution that assumes equal mutation rates among all four nucleotides. Under the supervision of Prof.

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Resolving conflict in eutherian mammal phylogeny using phylogenomics and the multispecies coalescent model

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基因树-物种树冲突

The reconstruction of the Tree of Life has relied almost entirely on concatenation methods, which do not accommodate gene tree heterogeneity, a property that simulations and theory have identified as

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Rational Design and Directed Evolution of E. coli Apartate Aminotransferase to Tyrosine Aminotransferase: Mutant P2.

蛋白质工程

定向进化

Rational Design and Directed Evolution of E. coli Apartate Aminotransferase to Tyrosine Aminotransferase: Mutant P2.

NIAID Data Ecosystem10

Long Branch Effects Distort Maximum Likelihood Phylogenies in Simulations Despite Selection of the Correct Model

系统发育树重建

长枝效应分析

The aim of our study was to test the robustness and efficiency of maximum likelihood with respect to different long branch effects on multiple-taxon trees. We simulated data of different alignment len

NIAID Data Ecosystem50

Data from: Maximum likelihood inference of small trees in the presence of long branches

系统发育树重建

长枝吸引

The statistical basis of maximum likelihood (ML), its robustness and the fact that it appears to suffer less from biases lead to it being one of the most popular methods for tree reconstruction. Despi

DataONE2015-08-19 更新20

Deep distributed computing to reconstruct extremely large lineage trees

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